Maxwell Sensor’s portable
FS-Scanner offers a fluorescence
detection approach to improve
rapid diagnostic testing.
Fluorescence detection offers
improved sensitivity
over
immunochromatography
Immunochromatography color
strips, used for rapid testing
of diseases or pathogens, is
based on visual inspection or
absorption measurement which has
been reported to have limited
sensitivity. Fluorescence
immunoassay (FIA) has become a
promising alternative in-vitro
diagnostic (IVD)method because
it offers better sensitivity in
comparison to the color strips.
The Fluorescence Strip Scanner
(FS-Scanner) is designed to scan
multiple samples with the
flexibility to use different
excitation and fluorescence
wavelengths for a variety of
fluorophores. The system can be
used for strip characterization
and can be customized with a
specific excitation light source
for IVD applications.
Rapid detection
The FS-Scanner is equipped with
a light source, optical fiber,
scanner, spectrometer, detector,
and software. The fluorescence
signal is carried through an
optical fiber probe into a
spectrometer and CCD for
spectral analysis. The scanner
scans a three-inch strip (with
or without a plastic cartridge)
with a spatial resolution of 0.1
mm in a few seconds.
Customizable
Push buttons (e.g., Control,
Test) are used to move the
optical probe directly to the
specific location. Since the
selection of excitation light
source and wavelength depends on
the choice of the fluorophore,
the light source used in the
system is changeable. The
generic FS-Scanner system is
facilitated with a red diode
laser with a wavelength at 635
nm for excitation.
Runs on a PC or laptop
The FS-Scanner requires an
external PC with a USB
connection for signal collection
and data processing. Both
fluorescence spectrum and
intensity are displayed on the
screen.
Top
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Strip format: |
1.0" x 4" x 0.5" with or
without plastic
cartridge. Configurable
to customer dimension. |
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Scan distance: |
3 inch |
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Scan spatial resolution:
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0.1 mm |
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Illumination spot size:
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1 mm |
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Fluorescence wavelength: |
300 ~ 1,000 nm in
spectral display |
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Dynamic range: |
Four decades |
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Optical detector: |
Linear CCD |
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Integration time: |
0.01 ~ 10.0 S
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Excitation light source: |
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♦ |
Diode laser 635 nm (5
-10 mW) |
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♦ |
LEDs
380nm, 475nm, 518nm,
590nm, 640nm (35-50µW)
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♦ |
Call for
other light sources
(Xenon, Deuterium, etc.), not included |
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Optical filter: |
Depends on the
wavelength selection |
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Interface & OS: |
USB to PC or Notebook
(PC or Notebook not
included); Windows XP,
2000 |
|
Software: |
CD with user friendly
software |
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Data output: |
Spectrum and Intensity |
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Power
requirement: |
115V, 60Hz |
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Dimension: |
12" L x
11" W x 4.5" H
(30cm L x 28cm W x 11cm
H) |
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Weight: |
7.5
lbs. (3.4 kgs.) |
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♦ |
Immunoassay (bacteria,
virus, toxin, and
pathogen) and proteomics
strip tests |
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Nucleic acid, DNA assay,
and Genomics strip tests |
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Rapid and point-of-care
clinical diagnostics |
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Food and environmental
tests |
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Biothreat agent and
toxin tests |
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Strip fabrication and
characterization tests |
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Clinical diagnostic
industry |
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IVD manufacturers |
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Hospital research
laboratories |
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Food industry |
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Environmental
testing |
